Sadie & Jesse’s Updates

Update on Jesse here in Washington at the NIH. Today marks a massive milestone in his journey — Day 100 post-transplant. This is the end of the...

Hi everyone, It’s been a little while since our last update, and we wanted to share where things are at on Jesse’s journey. Jesse is now on day 73...

South African endurance walker and philanthropist Gregg Mitchley set off today on a 600km journey from Johannesburg to Durban, marking the start of...

 Hi everyone,I wanted to share a meaningful update on Jesse’s progress since our last post.We’ve reached a really big milestone — Jesse has...

Hi everyone, I’d like to share another update on Jesse following our last post. (Day+31)After the previous update, Jesse was scheduled to have a...

Hi everyone,I just wanted to give a quick update on Jesse.Today is Day +21 after his transplant. The good news is that Jesse officially engrafted on...

Hi everyone, We wanted to share an update on Jesse as he reaches Day +6 after his bone marrow transplant for DOCK8 deficiency.The transplant itself...

The Krause family — Clayton, Lee-Ann, and Jesse — are now three weeks into the NIH program in Washington, DC. Jesse has undergone numerous medical...

In three days, Clayton and his family are flying to Washington DC, to the NIH. Since August, they've been waiting for a pathway and waiting for...

A suitable donor match has been identified for Jesse. The donor process follows established NIH transplant protocols used in the treatment of DOCK8...

For Jesse and his parents Clayton and Lee-Ann, the road ahead is not a single procedure, but a long, carefully managed medical journey that will...

As Jesse and his parents travel to the United States from 9 January, we invite you to follow our Facebook page, where Jesse and Sadie’s parents will...

We want to share an important and transparent update on Sadie and Jesse’s medical journey as we enter the next phase. While Sadie and Jesse share...

If you’ve been following DOCK8 stories online, you’ll notice something interesting: families often speak in the language of “breakthroughs,” “new...

To every single person who has supported our family, we want to say a heartfelt thank you. Over the past weeks, we have experienced a level of...

DOCK8 deficiency is not a single-symptom condition. It is a progressive, multisystem immune disorder that affects nearly every aspect of a child’s...

Families facing HSCT often ask why cost estimates vary so widely. The answer is that transplant is a process, not an event. Costs are influenced by:...

In rare disease journeys, awareness is about understanding. We’re sharing a recent article published by Independent Online that helps explain the...

In a truly heart-wrenching story of resilience and desperate hope, a family is battling to save their two young children diagnosed with one of the...

The past 2 weeks have been a tough one for the little ones. Both Sadie and Jesse started showing signs of flu, and for children living with DOCK8...

In DOCK8 deficiency, treatment decisions are not only about what to do, but when to do it. Transplant outcomes depend on multiple factors: The...

It’s been a tough few weeks. Things are moving slowly and the process of formalising a treatment plan has been incredibly challenging. Every step...

Families facing DOCK8 deficiency are often asked why doctors recommend stem cell transplantation so strongly and sometimes so early. The answer is...

From the bottom of our hearts - thank you. Every donation, message, and share has carried us through these incredibly tough months, and we’re so...

When a diagnosis is uncommon, there is often no roadmap, no local reference point, and very little public understanding of what families are facing...

One of the most visible and often misunderstood features of DOCK8 deficiency is severe viral skin disease. Among the most distressing examples is...

Thank you for the incredible kindness, messages, and generosity we’ve received. Your support has carried us through an incredibly difficult time,...

When people hear that a child has a “rare immune condition,” it can sound distant or abstract. DOCK8 immunodeficiency is neither. It is a severe,...